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观察硫酸依替米星治疗肿瘤病人化疗后感染的疗效。选择 32例肿瘤患者经化疗后 ,粒细胞降至1.0× 10 9/ L 以下伴有肺炎或败血症 ,或皮肤感染或尿路感染 ,其病原菌为金葡球菌、链球菌、大肠埃希氏菌、克雷伯氏菌、铜绿假单胞菌 ,使用硫酸依替米星 10 0 mg,静脉滴注 ,q12 h,疗程 7~ 10 d。结果粒细胞在 0 .5×10 9/ L 以上 ,有效率 92 .3% (2 4/ 2 6 ) ;粒细胞在 0 .5× 10 9/ L以下 ,有效率 3/ 6 ,总有效率 86 %。未见耳、肾毒性。结果表明 ,治疗肿瘤病人化疗后继发感染 ,硫酸依替米星是有效药物之一。
To observe the efficacy of etimicin sulfate in the treatment of cancer patients after chemotherapy. Select 32 cases of cancer patients after chemotherapy, neutrophils down to 1.0 × 10 9 / L following with pneumonia or sepsis, or skin infections or urinary tract infections, the pathogen Staphylococcus aureus, Streptococcus, Escherichia coli, Klebsiella, Pseudomonas aeruginosa, using etimicin sulfate 10 0 mg, q12 h, treatment of 7 ~ 10 d. Results Granulocytes were above 0.5 × 10 9 / L with an effective rate of 92.3% (24/26). Granulocytes were below 0.5 × 10 9 / L with an effective rate of 3/6. The total effective rate 86%. No ear, nephrotoxicity. The results show that the treatment of cancer patients after chemotherapy, secondary infection, etimicin sulfate is one of the effective drugs.