论文部分内容阅读
目的了解HIV感染后血清生化指标的变化,探讨HIV感染对机体组织的损伤程度。方法病例组为广西出入境人群发现的HIV感染者/AIDS患者,对照组为随机抽取的经广西口岸出入境正常人群。用全自动生化分析仪检测血清生化指标。结果各实验组ALT、ALP、BUN、Cre在正常范围;HBV/HCV/HIV混合感染组的AST明显高于HIV单感染组(P<0.01),而HIV单感染组与正常对照没有明显差异(P>0.05);各实验组γ-GT除吸毒传播感染组与正常对照没有明显差异(P>0.05)以外,其余各组都显著高于对照组(P<0.01);各实验组ALB除吸毒传播感染组与对照组没有明显差异(P>0.05)以外,其余各组都显著低于对照组(P<0.05)。结论单纯HIV感染对肝、肾组织似乎没有造成严重影响,HIV感染/AIDS者的白蛋白降低可能与慢性腹泻等消耗性疾病有关。
Objective To understand the changes of serum biochemical indexes after HIV infection and to explore the extent of damage to the tissues by HIV infection. Methods The case group was HIV infected persons / AIDS patients found in entry-exit population in Guangxi. The control group was randomly selected from the normal population of entry and exit of Guangxi. Serum Biochemical Indexes with Automatic Biochemical Analyzer. Results The levels of ALT, ALP, BUN and Cre in the experimental group were in the normal range. The levels of AST in the HBV / HCV / HIV mixed infection group were significantly higher than those in the HIV single infection group (P <0.01), while those in the HIV single infection group were not significantly different from those in the normal control group P> 0.05). There was no significant difference between the experimental group and the control group (P <0.01) except for the drug-infected transmission group of γ-GT and the control group (P> 0.05) There was no significant difference between the infected group and the control group (P> 0.05), the other groups were significantly lower than the control group (P <0.05). Conclusions Pure HIV infection does not appear to have a significant effect on liver and kidney tissues. The decrease of albumin in HIV / AIDS patients may be related to other chronic diseases such as chronic diarrhea.