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目的:观察枝黄止痛洗剂外洗联合负压封闭引流术治疗糖尿病足的微循环影响观察。方法:将60例Wagner分级2~4级的糖尿病足溃疡患者随机分为2组,治疗组30例采用枝黄止痛洗剂外洗联合负压封闭引流术及西药治疗;对照组30例采用负压封闭引流术及西药治疗。治疗4周后观察2组治疗情况。结果:2组治疗前后血浆黏度、红细胞压积、血小板聚集率比较,差异均有统计学意义(P<0.05)。2组治疗前后足背动脉经皮氧分压比较,差异有统计学意义(P<0.05);2组治疗后比较,差异有统计学意义(P<0.05)。2组治疗前后足背动脉血流量比较,差异有统计学意义(P<0.05);2组治疗后比较,差异有统计学意义(P<0.05)。结论:枝黄止痛洗剂外洗联合西医治疗糖尿病足溃疡对糖尿病足溃疡微循环改善效果良好。
OBJECTIVE: To observe the microcirculation effects of Zhilihuang Zhitong lotion combined with negative pressure closed drainage on diabetic foot. Methods: Sixty Wagner patients with grade 2-4 diabetic foot ulcers were randomly divided into two groups. 30 cases in the treatment group were treated with Zhixintongshong lotion combined with negative pressure drainage and Western medicine. In the control group, 30 cases were negative Pressure closure drainage and Western medicine treatment. After 4 weeks of treatment, the treatment of 2 groups was observed. Results: There were significant differences in plasma viscosity, hematocrit and platelet aggregation between the two groups before and after treatment (P <0.05). The difference of transcutaneous oxygen pressure between the two groups before and after treatment was statistically significant (P <0.05). There was significant difference between the two groups after treatment (P <0.05). The blood flow of the dorsalis pedis artery between the two groups before and after treatment was significantly different (P <0.05). There was a significant difference between the two groups after treatment (P <0.05). Conclusion: Huanghuang Zhitong lotion combined with Western medicine treatment of diabetic foot ulcer microcirculation of diabetic foot ulcer improved good effect.