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目的:探讨糖调节受损(IGR)患者颈动脉中膜厚度(IMT)增加的危险因素。方法:统计76例IGR患者及51例正常糖耐量(NGT)人的年龄、性别、体质量、血压、测空腹血糖、餐后2小时血浆血糖(OGTT)、空腹甘油三酯、总胆固醇(TC)、低密度脂蛋白(LDL-C)、高密度脂蛋白(HDL-C),并计算体重指数,检测颈动脉中膜厚度(IMT)值。分析不同IGR患者IMT值的差异性。结果:IGT组及IFG+IGT组IMT分别与IFG组及NGT组比较有显著差异(P<0.05),其他各组比较无显著差异。年龄、收缩压、TC、LDL-C、2hPG是IMT的危险因素。结论:与NGT组比较,IGT组、IFG+IGT组患者早期已存在明显的动脉粥样硬化(AS)及与之相关的危险因素。
Objective: To investigate the risk factors of carotid intima-media thickness (IMT) in patients with impaired glucose regulation (IGR). Methods: The age, sex, body weight, blood pressure, fasting blood glucose, 2-hour postprandial plasma glucose (OGTT), fasting triglyceride and total cholesterol (TC) in 76 IGR patients and 51 normal glucose tolerance (NGT) ), LDL-C and HDL-C, and body mass index (BMI) were calculated. The carotid intima-media thickness (IMT) was measured. To analyze the differences of IMT values in different IGR patients. Results: IMT in IGT group and IFG + IGT group were significantly different from those in IFG group and NGT group (P <0.05). There was no significant difference in other groups. Age, systolic blood pressure, TC, LDL-C, 2hPG are risk factors for IMT. Conclusion: Compared with NGT group, obvious atherosclerosis (AS) and related risk factors existed in IGT group and IFG + IGT group at early stage.