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本文对174例肺癌患者1:2配对调查的结果表明:吸烟者患肺癌的RR为2.34,其中男性RR为2.47、女性RR为2.05,存在剂量反应关系,肺癌组与对照组的RR均有明显差别,其RR随吸烟量的增加而增加,其比例亦逐渐增加,尤其是大量吸烟(≥20支/天)与<20支/天及不吸烟者之间有极显著差别。开始吸烟年龄与肺癌有关,吸烟年龄组越小者,得肺癌的RR越大,如10岁~组的RR最高为2.47,其比例亦最高为0.80,开始吸烟年龄≥19岁与<19岁及不吸烟者比较有显著差别。吸烟年限与癌肺亦有关系,吸烟年限越长其RR越大,肺癌与对照的比例也越大,尤其是吸烟年限≥31年与<30年及不吸烟者比较,均有显著差别。环境污染因素中,肺癌患者住地环境空气中NO_2的浓度比健康人群高1~6倍,SO_2第四季度高2倍;与生活用煤柴无关,但与通风是否良好有关;说明吸烟是得肺癌的最主要因素,环境亦起重要作用。
The results of a 1: 2 paired survey of 174 patients with lung cancer showed that the RR of smokers with lung cancer was 2.34, with a male RR of 2.47 and a female RR of 2.05, with a dose-response relationship. The RR of lung cancer patients and control patients was significantly The RR increased with the increase of the amount of smoking, the proportion also increased gradually, especially the large number of smoking (≥ 20 / day) and <20 / day and non-smoker were significantly different. The age of onset of smoking is related to lung cancer. The smaller the smoking age group, the greater the RR of lung cancer. For example, the highest RR of 2.47 in the 10-year-old group was 0.80, the highest was 0.80, and the smoking age was 19 or older and 19 or Non-smokers are more significant differences. Smoking duration and cancer also have a relationship, the longer the smoking life, the greater the RR, the greater the proportion of lung cancer and control, especially the smoking duration of 31 years and 30 years and non-smokers were significantly different. Among the environmental pollution factors, the concentration of NO 2 in the ambient air of lung cancer patients was 1 to 6 times higher than that of healthy people and twice as high as that of SO 2 in the fourth quarter; it was not related to the use of coal-wood for life, but it was related to the good ventilation; The environment also plays an important role.