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目的:研制乙酰螺旋霉素口腔糊剂。方法:以黏附力、吸水值和赋形性为指标优选高分子材料的品种、用量,并进行稳定性试验和药效学试验。结果:处方组成合理,制备工艺可行。结论:该糊剂质量稳定,使用方便,疗效确切。
Objective: To develop acetylspiramycin oral paste. Methods: The types and dosage of macromolecule materials were optimized by the indexes of adhesion, water absorption and formability. The stability and pharmacodynamics were tested. Results: The prescription is reasonable and the preparation process is feasible. Conclusion: The quality of the paste is stable, easy to use and effective.