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采用ELISA法检测了37例流行性出血热(EHF)患者血浆VWF水平,发现VWF水平在发热期即已升高,至少尿期达高峰,多尿期开始恢复;重度出血者VWF水平显著升高。结果提示进行血浆VWF水平的检测有利于判断病情,估计预后。
The plasma VWF levels in 37 patients with epidemic hemorrhagic fever (EHF) were measured by ELISA. It was found that VWF levels increased during the febrile period, reached the peak in at least the urine phase, and started to increase in the polyuria stage. The VWF level in patients with severe hemorrhage was significantly increased . The results suggest that the detection of plasma VWF level is conducive to assess the disease, prognosis.