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应用ELISA法检测了125例心、脑血管疾病患者及28例健康者血中氧化型低密度脂蛋白(oxLDL)及脂蛋白a〔LP(a)〕,结果表明脑梗塞、脑出血及冠心病三组疾病oxLDL及LP(a)含量显著高于对照组(P<0.01),其阳性率亦高于对照组,尤以脑梗塞最为显著,oxLDL及LP(a)阳性率高达76.3%和73.7%,结果说明oxLDL及LP(a)与心、脑血管疾病发生有关,本方法可以做心、脑血管疾病的辅诊手段之一。
The levels of oxidized low density lipoprotein (oxLDL) and lipoprotein A (LP (a)) in 125 patients with cardiac and cerebrovascular diseases and 28 healthy controls were detected by ELISA. The results showed that cerebral infarction, cerebral hemorrhage and coronary heart disease The levels of oxLDL and LP (a) in the three groups were significantly higher than those in the control group (P <0.01). The positive rates of oxLDL and LP (a) in the three groups were also higher than those in the control group. 3% and 73.7%, the results show that oxLDL and LP (a) and cardiovascular and cerebrovascular diseases, the method can do heart and cerebrovascular disease diagnosis of one of the means.