Cytochromes P450 are a superfamily of monooxygenases that are found in all kingdoms of life and which show extraordinary diversity in their reaction chemistry.T
The CYP74 enzymes (allene oxide synthases (AOSs), hydroperoxide lyases (HPLs), divinyl ether synthases (DESs)) are non-classical cytochromes P450 which play an
The rates of protein conformational changes are not only limited by external but also internal friction, however, the origin and significance of this latter phe