论文部分内容阅读
在口蹄疫灭活疫苗的生产中BHK-21细胞的生产是整个产品生产中的重要环节,在目前生产上由于所用培养基价格的昂贵,所以生产1瓶细胞(瓶子的容积是1.5万mL)的成本价是30.00元,细胞的生产成本约占产品成本的40%。因此如何降低细胞生产成本是口蹄疫灭活疫苗生产者不断追求的课题,为此我们在改进细胞生产工艺,提高细胞合格率方面进行了大胆尝试,经过三年多的生产实践证明,用改进后的工艺生产细胞不仅在细胞合格率方面获得提高而且也降低了细胞制作成本。
The production of BHK-21 cells in the production of FMD vaccine is an important part of the whole product production. In the current production, due to the high price of the medium used, 1 bottle of cells (the volume of the bottle is 15000 mL) The cost price is 30.00 yuan, cell production costs account for about 40% of product costs. Therefore, how to reduce the cost of cell production is the constant pursuit of FMD vaccine producers. To this end, we have made a bold attempt to improve the cell production technology and improve the cell pass rate. After more than three years of production practice, Processed cells are not only improved in terms of cell pass rates but also reduce cell production costs.