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目的与单用利凡诺引产比较,观察米非司酮配伍利凡诺用于中期妊娠引产的效果。方法选择妊娠13～24周要求引产的妇女144例随机分为两组:对照组72例直接羊膜腔内注射利凡诺100 mg;观察组72例在应用利凡诺基础上,配伍米非司酮引产(50 mg/次,每12小时1次,总量为150 mg)。比较两组的引产时间、并发症、引产效果。结果与对照组相比,观察组胎盘胎膜残留发生率(5.56%vs 25.00%,P<0.01)及合并症总发生率明显降低(5.56%vs 34.72%,P<0.01),且引产时间缩短(P<0.01);引产成功率有所提高,但差异无统计学意义(P>0.05)。结论米非司酮配伍利凡诺引产方法简便、安全、效果好,是中期妊娠引产较为理想的方法。
Purpose and rivanol induced labor alone compared to observe the effect of mifepristone with rivanol for induction of labor in the second trimester of pregnancy. Methods 144 women who required induction of labor at 13-24 weeks of gestation were randomly divided into two groups: 72 cases in the control group were given rivanol 100 mg directly by intra-amniotic injection; 72 cases in the observation group were treated with rivanol Keto labor (50 mg / time every 12 hours, a total of 150 mg). Compare the two groups of induction of labor time, complications, induction of labor. Results Compared with the control group, the incidence of residual fetal membranes in the observation group (5.56% vs 25.00%, P <0.01) and the overall incidence of complications were significantly lower (5.56% vs 34.72%, P <0.01) (P <0.01). The success rate of induction of labor was increased, but the difference was not statistically significant (P> 0.05). Conclusions Mifepristone compatibility rivanol induction method is simple, safe and effective, and it is an ideal method for induction of labor in the second trimester of pregnancy.