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抗凝剂所致出血的部位和临床特征颇有差异。幸而引起梗阻的上呼吸道出血罕见。华法令钠(sodium warfarin)引起咽后壁出血和呼吸道梗阻者曾有报导。本文报告了第1例继发于华法令钠治疗引起的舌根、会厌自发性出血致急性上呼吸道梗阻。患者为41岁妇女,因风湿性二尖瓣狭窄接受了二尖瓣置换手术以后,9年来每日用洋地黄、利尿剂和华法令钠5～10mg。住院前4天曾患轻度上呼吸道感染,住院当天早晨剧咳后发生咽喉痛、颈部肿胀及呼吸困难,不能平卧。无颈部外伤史。口腔检查发现舌根、会厌谷
Anticoagulant bleeding caused by the site and the clinical features are quite different. Fortunately, upper respiratory tract obstruction caused by rare. There have been reports of sodium warfarin causing back pharyngeal hemorrhage and airway obstruction. This article reports the first case of acute upper respiratory tract obstruction caused by the spontaneous bleeding of the tongue base and epiglottis caused by treatment with warfarin sodium. The patient, 41 years old, had digitalis, diuretics and warfarin sodium 5 to 10 mg daily for nine years after receiving mitral valve replacement for rheumatic mitral stenosis. 4 days before hospitalization had mild upper respiratory tract infection, cough, sore throat after hospitalization the morning of the same day, neck swelling and breathing difficulties, can not be supine. No history of neck trauma. Oral examination found tongue base, will be tired of the valley