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目的研制一种新型复方中草药抑菌漱口液及其抑菌效果。方法采用纸片扩散法,对该新型复方中草药口服液体外抑菌效果进行了观察。结果经过筛选确认该复方中草药口服液组方含黄芩1 000 mg/ml与黄柏125mg/ml或黄芩500 mg/ml与黄柏2 000 mg/ml。纸片扩散法试验证明,所选出的复方中草药口服液对变异链球菌、乳酸杆菌有明显抑菌作用。该新型复方中草药抑菌漱口液对乳酸杆菌和变异链球菌的MIC值黄芩为62.5 mg/ml、黄柏为7.812 mg/ml。结论含黄芩、黄柏的新型复方中草药抑菌漱口液可以有效抑制变异链球菌和乳酸杆菌。
Objective To develop a new compound Chinese herbal medicine antibacterial gargle and its bacteriostatic effect. Methods The antibacterial effect of Oral Liquid of this new compound Chinese herbal medicine was observed by disk diffusion method. Results The screening confirmed that the compound Chinese herbal medicine oral solution containing Scutellaria baicalensis 1000 mg / ml and Treats 125mg / ml or Scutellaria 500 mg / ml and Treats 2000 mg / ml. Paper diffusion test proved that the selected compound Chinese herbal medicine oral liquid Streptococcus mutans, Lactobacillus obvious inhibitory effect. The new compound Chinese herbal antibacterial mouthwash against Lactobacillus and Streptococcus mutans MIC value Scutellaria 62.5 mg / ml, Treats 7.812 mg / ml. Conclusion The new compound Chinese herbal medicine containing Scutellaria baicalensis and Phellodendron chinense can inhibit S. mutans and L. lactis effectively.