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在失血性与内毒性休克家兔中,利用免疫单扩和双扩法分别测定家兔休克前后不同时间血浆内Fn含量。结果表明,在失血性休克中,休克30分钟时,血浆内Fn有显著性下降,以后随着休克的发展,持续降低。休克30分钟时将血液回输.血压恢复,Fn含量也随之上升。在内毒素性休克中,休克30分钟时,与休克前比较,血浆Fn含量有显著性的升高,休克60分钟时,血浆Fn含量显著降低,后者60分钟变化与失血性休克相同。对上述变化可能发生机制进行了讨论。
In hemorrhagic and endotoxic shock rabbits, single immunodiffusion and double-expansion method were used to determine the plasma Fn levels at different time points before and after shock in rabbits. The results showed that in hemorrhagic shock, shock at 30 minutes, Fn in plasma decreased significantly, with the development of shock after continued decline. Shock 30 minutes when the blood back to the blood pressure recovery, Fn content also will rise. In endotoxic shock, the level of Fn in plasma increased significantly at 30 minutes of shock compared with that before shock, and was significantly lower at 60 minutes of shock, with the latter 60 minutes changing in the same way as hemorrhagic shock. Possible mechanisms for the above changes are discussed.