尖锐湿疣作为一种性传播疾病,诊断应慎重。由于假性湿疣、乳头状瘤等与之在光镜下相似,可造成漏诊、误诊。组织中人乳头状瘤病毒(ＨＰＶ)检测能反映其感染,但不能取代病理学检查及诊断[1,2]。本文参照廖松林、陈乐真等[3,4]标准进行病理形态学分析,结合ＨＰＶ-Ⅰ免疫组化检测结 Condyloma acuminatum as a sexually transmitted disease, the diagnosis should be careful. Due to pseudo-genital warts, papillomas and the like with the light microscope, can cause missed diagnosis, misdiagnosis. Human papillomavirus (HPV) detection in tissue can reflect the infection, but can not replace the pathological examination and diagnosis [1,2]. In this paper, Liao Songlin, Chen Lezhen et al [3,4] standard pathomorphological analysis, combined with HPV-I immunohistochemistry test results