患者为4岁男孩。生后2～3个月逐渐出现杵状指(趾)。颜面和头皮出现湿疹,皮肤增厚,前额皮肤有皱褶,多汗,特别是指(趾)明显。2岁出现双膝、踝关节肿胀、疼痛。本病的病因和发病机理至今不清。国内外资科报导,多数有家族史,同胞中可数人发病。这说明该病可能为常染色体显性遗传。 Patient is 4 year old boy. 2 to 3 months after birth gradually clubbing fingers (toes). Eczema on the face and scalp, thickening of the skin, wrinkles on the forehead, sweating, especially on the toe. 2 years old appear knees, ankle swelling, pain. The etiology and pathogenesis of this disease is unclear. Domestic and foreign information section, most have a family history, the number of people in the compatriots. This shows that the disease may be autosomal dominant.