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目的:探讨自体血液回输在异位妊娠腹腔出血临床手术治疗中的安全性及有效性。方法:选择2008年1月~2014年12月在该院妇科确诊为异位妊娠并经腹腔镜手术的32例患者,于术中采用洗涤式自体血液回输,监测患者自体血回输前后红细胞压积、红细胞计数、血红蛋白含量、血小板、凝血功能及肝、肾功能的变化,观察其输血后有无不良反应。结果:32例患者腹腔内出血量为600~2 300 ml,平均(1 250±285)ml,自体回输血量为300~1 200 ml,平均(850±150)ml,与术前比较,患者术后第1天血红蛋白、红细胞、红细胞压积等均有一定程度的升高,差异均有统计学意义(P<0.05),血小板、凝血及肝肾功能无明显变化(P>0.05),未出现不良反应。结论:异位妊娠患者腹腔镜术中采用洗涤式自体血液回输安全、有效,既可节约血源,又可降低输注异体血的风险。
Objective: To investigate the safety and efficacy of autologous blood transfusion in the clinical surgical treatment of ectopic pregnancy with intraperitoneal hemorrhage. Methods: Thirty-two patients with gynecologic diagnosis of ectopic pregnancy and laparoscopic surgery from January 2008 to December 2014 in our hospital were treated with wash-back autologous blood transfusion during operation and red blood cells were monitored before and after autologous blood transfusion Pressure, erythrocyte count, hemoglobin content, platelet, coagulation and liver and kidney function changes, to observe whether the adverse reactions after transfusion. Results: The intra-abdominal hemorrhage volume of 32 patients was 600-2 300 ml with an average of (12 250 ± 285) ml and autologous transfusion volume was 300-1 200 ml with an average of (850 ± 150) ml. Compared with preoperative, The hemoglobin, erythrocyte and hematocrit increased to a certain extent on the first day after the operation, with statistical significance (P <0.05), no significant changes in platelet, coagulation and liver and kidney function (P> 0.05) Adverse reactions. Conclusions: Laparoscopic surgery in patients with ectopic pregnancy using washed self blood transfusion safe and effective, can save blood, but also reduce the risk of allogeneic blood transfusion.