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我院于1983年10月及1984年11月收治婴幼儿急性胃肠炎63例,重点探讨了:1.病原,应用酶联免疫吸附试验——ELISA方法,对其中57例粪便进行轮状病毒检测,阳性率为39/57(68.4%);2.流行病学,具有明显的流行性与季节性,发病年龄最小3月,最大2岁,其中6月～1 1/2岁者发病率为82.5%,混合喂养与人工喂养儿发病率为66%;3.临床特点,病初伴有发热者68.4%、上呼吸道感染者44.4%,全部病例均具有典型腹泻和呕吐,且有轻至中度脱水及酸中毒;4.免疫状态,患儿粪便SIgA降低,血清IgM升高,IgG降低,E-RFC形成率降低,均与正常儿有显著差异。
In our hospital in October 1983 and November 1984 admitted 63 cases of acute gastroenteritis in infants and young children, focusing on: 1. Pathogen, the application of enzyme-linked immunosorbent assay - ELISA method, of which 57 cases of rotavirus rotavirus The positive rate was 39/57 (68.4%). 2. Epidemiology, with obvious epidemiology and seasonality, the minimum age of onset was 3 months and the maximum was 2 years, of which the incidence rate was between 6 months and 1 1/2 years Was 82.5%. The incidence of mixed feeding and artificial feeding was 66%. 3. Clinical features: 68.4% of the patients were fever and 44.4% of the upper respiratory tract infections in the early stage. All the cases had typical diarrhea and vomiting, Moderate dehydration and acidosis; 4 immune status, SIgA drop in children with stool, serum IgM increased, IgG decreased, E-RFC formation rate decreased, were significantly different from normal children.