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为进一步观察血清免疫球蛋白Ｅ（ＩｇＥ）在甲型肝炎病毒（ＨＡＶ）及乙型肝炎病毒（ＨＢＶ）感染者血清中变化，作者对９０例ＨＡＶ、ＨＢＶ感染者进行检测。结果２４例急性甲肝中ＩｇＥ增高１６例（６６．６７％），６例急性乙肝中ＩｇＥ增高５例（８３．３３％），两者与标准值相比较呈显著差异。３０例慢性乙肝及３０例ＨＢＶ携带者中ＩｇＥ增高分别是９例（３０％）和１０例（３３％），两者与标准值相比无显著差异，但与急性肝炎相比呈显著差异。通过观察发现血清ＩｇＥ增高与血清谷丙转氨酶（ＡＬＴ）增高呈正相关，与所感染的病毒分型关系不大。可认为ＩｇＥ不失为急性肝损害的灵敏指标之一。
In order to further observe the changes of serum IgE in the sera of hepatitis A virus (HAV) and hepatitis B virus (HBV) infected persons, 90 cases of HAV and HBV infection were detected. Results The serum IgE in 24 cases of acute hepatitis were increased in 16 cases (66.67%) and in 6 cases of acute hepatitis B in 5 cases (83.33%). There was a significant difference between them and the standard value. IgE in 30 chronic hepatitis B patients and 30 HBV carriers were 9 cases (30%) and 10 cases (33%) respectively. There was no significant difference between the two groups in the standard value, but significant difference compared with acute hepatitis. Through observation, it was found that the increase of serum IgE was positively correlated with the increase of serum alanine aminotransferase (ALT) and had little to do with the type of virus that was infected. IgE can be considered one of the sensitive indicators of acute liver damage.