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报道了无外加配体参与的以吡唑作为导向基团的铱催化的sp3碳氢键的区域选择性硼化反应.在催化量的[Ir(OMe)(cod)]2存在下,该反应能够顺利地将苄位的二级碳氢键转化成碳硼键.该反应具有非常广谱的官能团兼容性,能够以良好到优秀的产率生成相应的产物.此外,导向基团吡唑能够通过臭氧接转化成酰胺.“,”The ligand-free regioselective iridium-catalyzed C(sp3)—H bond borylation using pyrazole as the directing group is reported.The reaction occurs smoothly at the secondary benzylic position in the presence of a catalytic amount of commercially available[Ir(OMe)(cod)]2.A variety of functionalities could be well tolerated,affording corresponding products in good to excellent yields.The pyrazole could be degraded into amide by ozonolysis.