论文部分内容阅读
脂质体是目前在体外实验中能将各种物质引入细胞内的最有效的载体,它可以作为水溶性和脂溶性物质的载体。现已有数百种不同的物质可包被于脂质体中,其中包括酶、糖脂、免疫球蛋白、单克隆抗体、药物(尤其是抗肿瘤、抗关节炎和抗寄生虫药物)、抗原、生物反应调节剂(如淋巴因子和胞壁酰二肽)、抗真菌药物、螯合剂、标记物、抗生素、离子、疫苗和染色体。定义脂质体是人工磷脂类囊泡。根据纽约科学院提出的定义,脂质体有下列三种:多层大囊泡(MLV),其大小为0.1～5μm;小单
Liposomes are currently the most effective carriers for introducing various substances into cells in in vitro experiments, and can serve as a carrier for water-soluble and lipophilic substances. Hundreds of different substances are now available for encapsulation in liposomes, including enzymes, glycolipids, immunoglobulins, monoclonal antibodies, drugs (especially anti-tumor, anti-arthritic and anti-parasitic drugs) Antigens, biological response modifiers such as lymphokines and muramyl dipeptides, antifungal drugs, chelators, labels, antibiotics, ions, vaccines and chromosomes. Liposomes are defined as artificial phospholipid vesicles. According to the definition of New York Academy of Sciences, liposomes have the following three kinds: large vesicles (MLV), its size is 0.1 ~ 5μm; small single