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为研究冠状动脉内膜增厚的年龄性改变及其与动脉粥样硬化发生发展的关系。应用Ｑｕａｍｔｉｍｅｎｔ９７０图像分析仪对北京地区１０２例意外死亡年轻人（１５～３９岁）冠状动脉近侧端进行了形态定量及统计学处理。结果是，内膜增厚随年龄增长而增加，男厚于女，在同体三支冠脉的比较研究中内膜增厚的速度与程度均以左前降支居首位，依次为右冠状动脉和左旋支。两性２０～２４岁内膜增厚速度及平均年递增率较快，２５～３４岁的十年间渐趋平稳，男性３５～３９岁及女性３０～３４岁再次出现增厚高峰．前者管腔狭窄率达５７．４％。内膜增厚的形态呈弥漫性和偏心性。本研究提示内膜增厚的年龄性改变是从生理性向病理性发展的过程，是动脉粥样硬化形成的组织学基础，也为动脉粥样硬化和冠心病的预防及诊断提供了重要的形态学依据．
To study the age-related changes of coronary intimal thickening and its relationship with the development of atherosclerosis. The Quamtiment970 image analyzer was used to determine the morphological and coronary artery proximal end of 102 accidental deaths in Beijing (15-39 years old). As a result, intimal thickening increased with age, male thicker than female, compared with three in the same coronary artery intimal thickening speed and degree of left anterior descending in the first place, followed by the right coronary artery And left-sided branch. The rate of endometrial thickening and the average annual increase rate of 20- to 24-year-old in both sexes were relatively fast. The average age of 25-34 years tended to be steady. The peak of thickening appeared again in males aged 35-39 and females aged 30-34 years. The former lumen stenosis rate of 57.4%. Endometrial thickening of the form was diffuse and eccentric. This study suggests that age-related changes in intimal thickening from the pathophysiological to pathological development of atherosclerosis is the formation of histological basis, but also for the prevention and diagnosis of atherosclerosis and coronary heart disease provides an important form Learn from.