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目的 :探讨CT引导下肺穿刺治疗重症空洞型肺结核的疗效。方法 :选取2011年3月~2016年4月我院收治的60例重症空洞型肺结核患者作为研究对象,根据治疗方案将上述研究对象分为对照组(26例)与观察组(34例),对照组接受常规化疗方案治疗,观察组则在常规化疗方案基础上再联合使用CT引导下肺穿刺空洞注入抗结核药物治疗,疗程结束后对比分析两组患者的疗效。结果 :观察组治疗结束后痰菌转阴率(76.47%vs 42.31%)、病灶显著吸收率(61.76%vs 30.77%)显著高于对照组,差异有显著性。观察组治疗结束后空洞情况显著优于对照组,差异有显著性。观察组空洞内存在液平的比例显著低于对照组(5.88%vs 46.15%),差异有显著性。两组患者均未发生严重不良反应,仅观察组有1例患者出现痰中少许血丝,未经特殊处理后1周内消失。结论 :CT引导下肺穿刺治疗重症空洞型肺结核的疗效确切,且安全性良好。
Objective: To investigate the effect of CT-guided pulmonary puncture in the treatment of severe pulmonary tuberculosis. Methods: From March 2011 to April 2016, 60 patients with severe pulmonary tuberculosis admitted in our hospital were selected as the research objects. According to the treatment plan, the above subjects were divided into control group (26 cases) and observation group (34 cases) The control group received routine chemotherapy regimen. The observation group was treated with CT-guided emptying of anti-tuberculosis drugs by the combination of conventional chemotherapy regimen. After treatment, the curative effect of the two groups was compared. Results: After the treatment, the rate of sputum negative conversion (76.47% vs 42.31%) in the observation group was significantly higher than that in the control group (61.76% vs 30.77%), the difference was significant. The observation group after the end of the cavity was significantly better than the control group, the difference was significant. There was a significant difference in the level of vacuoles in the observation group compared with the control group (5.88% vs 46.15%). No serious adverse reactions occurred in both groups, only one patient in observation group had a little bloodshot in sputum and disappeared in 1 week without special treatment. Conclusion: CT-guided pulmonary puncture for the treatment of severe pulmonary tuberculosis is effective and safe.