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本文以围着床期为焦点探讨妊娠的免疫学维持机构。此期的母子相关免疫有胚胎的抗原性、围绕胚胎的环境因子、胚胎与子宫内膜的免疫信息交换、子宫内膜担任免疫细胞等的特殊变化,着床的生理机构以及围着床期受精卵的死灭等,与着床障碍有密切关系。移植免疫反应由向心性和离心性途径构成。前者识别非自体移植物的主要组织适合性基因复合物(MHC)——相容免疫机构而开始反应;后者排除(排异反应)或容受(相容反应)移植物。首先移植物的移植抗原被相容的巨噬细胞等抗原提示细胞所识别,提示给辅助T细胞(T_11细胞),继之担
This article focuses on the bedtime as the immunological maintenance organization of pregnancy. The mother-child immunization during this period has the antigenicity of the embryo, the environmental factors surrounding the embryo, the immune information exchange between the embryo and the endometrium, the special changes of the endometrium as immune cells, the physiological mechanism of implantation, The death of eggs, etc., and implantation disorders are closely related. Immune response to transplantation by the centripetal and centrifugal pathways. The former recognizes the major histocompatibility complex (MHC) -compatible immune machinery of a non-autograft to initiate the reaction; the latter excludes (rejection) or tolerates (compatibilizes) the graft. First, graft transplanted antigens are recognized by antigen-presenting cells such as compatible macrophages, suggesting that helper T cells (T-11 cells)