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蛋白质芯片是一种新型的高通量蛋白质组学技术,由于其具有高通量、微型化、可平行快速分析等优点,因此在肿瘤血清标识物发现研究方面具有广泛的应用前景。本文综述了蛋白质芯片的基本原理、类型及其在肿瘤血清标记物发现研究中的应用,将蛋白质芯片技术与传统的肿瘤标志物发现技术进行了比较,并对蛋白质芯片技术在肿瘤标识物发现研究上的进一步应用进行了展望。
Protein chip is a new high-throughput proteomics technology. Because of its advantages of high throughput, miniaturization and parallel rapid analysis, protein chip has wide application prospects in tumor serum marker discovery research. This review summarizes the basic principle and type of protein chip and its application in the discovery of tumor serum markers. The technology of protein chip is compared with the traditional techniques of tumor marker discovery. The application of protein chip technology in the discovery of tumor markers On the further application of the outlook.