目的 观察路泰治疗晚期癌症疼痛的效果。方法 采用美国路坦医药公司的新型硫酸吗啡缓释片即路泰,应用于85例中重度癌痛患者,用量为10～60mg/次,隔12小时口服一次。结果 路泰对中度癌痛者,有效率为90.5％(19/21),重度癌痛者为93.8％(60/64).总有效率为92.9％(69/85),常见副作用为恶心呕吐、嗜睡,头昏、便秘等。结论 该药作为晚期癌痛患者止痛治疗,疗效好,服用方便,安全,无成瘾性及呼吸抑制现象。 Objective To observe the effect of Lu Tai on advanced cancer pain. Methods Lutai, a novel morphine sulfate sustained-release tablet, was used by the American Lutan Pharmaceutical Co., Ltd., and it was applied to 85 patients with moderate to severe cancer pain. The dosage was 10-60 mg/time and was administered once every 12 hours. Results The results showed that the effective rate was 90.5% (19/21) for patients with moderate degree of cancer pain, and 93.8% (60/64) for patients with severe cancer pain. The total effective rate was 92.9% (69/85). Common side effects were nausea. Vomiting, drowsiness, dizziness, constipation, etc. Conclusion As an analgesic treatment for patients with advanced cancer pain, the drug has good curative effect, convenient administration, safety, no addiction and respiratory depression.