论文部分内容阅读
近年来陆续有一些关于短期大量口服硝苯吡啶(180mg/日以上)引起糖耐量下降,导致血糖升高的报道。但长期小剂量应用硝苯吡啶(20～30mg/日)能否产生糖耐量异常尚未见报道。本文对649名58岁以上长期应用小剂量硝苯吡啶的老年人进行了用药调查,以探讨其对糖代谢的影响。 本文共观察649例,均为男性。年龄58～81岁,平均年龄65岁。其中冠心病178例,高血压病88例,诊断符合全国内科学术会议冠心病及高血压病的诊断标准,其余383例为健康老年人。共分三组:
In recent years, there are some reports on the short-term large amount of oral nifedipine (180mg / day or more) caused by decreased glucose tolerance, leading to elevated blood glucose reports. However, long-term low-dose application of nifedipine (20 ~ 30mg / day) can produce glucose tolerance abnormalities have not been reported. In this paper, 649 elderly over the age of 58 long-term use of small doses of nifedipine drug use survey to investigate its impact on glucose metabolism. This article observed a total of 649 cases, all men. Age 58 to 81 years, mean age 65 years. Among them, 178 cases of coronary heart disease and 88 cases of hypertension were diagnosed in accordance with the diagnostic criteria of coronary heart disease and hypertension in the national medical conference, and the remaining 383 cases were healthy elderly. Divided into three groups: