小儿急性毛细支气管炎雾化吸入硫酸沙丁胺醇与静滴甲基强的松龙临床疗效比较

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目的:观察硫酸沙丁胺醇氧驱动雾化吸入治疗及甲基强的松龙静滴小儿急性毛细支气管炎的临床疗效。方法::选取226例急性毛细支气管炎患儿为观察对象,按照入院顺序随机均分为第一组80例第二组79例和第三组67例,三组患儿入院后均给予常规治疗方法,第一组加用硫酸沙丁胺醇氧驱动雾化吸入治疗,第二组加用甲基强的松龙静滴治疗,第三组不予特殊治疗。治疗1周后观察疗效。结果:第一组患儿总有效率为90.3%明显高于第二组总有效率72.2%及第三组总有效率62.7%,三组总有效率比较差异有统计学意义。第一组患儿住院天数(4.5±1.2)天,明显短于第二组(8.9±1.6)天及第三组(9.1±1.5),三组比较差异有统计学意义。(P<0.05)。结论:硫酸沙丁胺醇相对甲基强的松龙静滴治疗小儿急性毛细支气管炎起效快,作用强,疗效好,安全性高,操作简便,值得临床推广应用。 Objective: To observe the clinical efficacy of salbutamol sulfate aerosol inhalation and methylprednisolone infusion in children with acute bronchiolitis. Methods: A total of 226 children with acute bronchiolitis were enrolled in this study. They were randomly divided into the first group of 80 cases, the second group of 79 cases, and the third group of 67 cases. The three groups were given routine treatment Methods: The first group was treated with salbutamol sulfate aerosol inhalation, the second group with methylprednisolone infusion therapy, the third group without special treatment. One week after treatment, the curative effect was observed. Results: The total effective rate was 90.3% in the first group was significantly higher than the total effective rate of 72.2% in the second group and 62.7% in the third group, the total effective rate was statistically significant difference between the three groups. The hospitalization days in the first group (4.5 ± 1.2 days) were significantly shorter than those in the second group (8.9 ± 1.6) days and the third group (9.1 ± 1.5). The differences between the three groups were statistically significant. (P <0.05). Conclusion: Salbutamol sulfate relative to methylprednisolone treatment of children with acute bronchiolitis rapid onset of rapid action, strong effect, good effect, high safety, easy to operate, it is worthy of clinical application.
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