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目的研究并行采集(SENSE)技术联合平面回波扩散加权像(EPI-DWI)技术在具有磁化率伪影的脑梗死中的应用。方法收集38例装有固定金属假牙脑梗死的患者资料,其中男性22例,女性16例;年龄52~86岁,平均年龄72岁。均行MRI头颅平扫、弥散加权成像(DWI)与SENSE-EPI-DWI。比较分析使用SENSE技术前后的右侧基底节区与右侧侧脑室脑脊液两者的信号强度对比度(SIR)(均数±标准差)、对比噪声比(CNR)、SIR、正常小脑表面扩散系数(ADC)值、梗死灶/健侧脑组织的ADC比值。结果①SENSE-EPI-DWI的右侧基底节区与右侧侧脑室脑脊液两者的SIR的均数±标准差高于常规EPI-DWI的序列(0.810 0±0.386 3 vs 0.610 0±0.468 7;t=9.872,P<0.05);②SENSE-EPI-DWI的CNR均高于常规EPI-DWI的CNR(11.622 5 vs 4.385 3;t=6.615,P<0.05);③SENSE-EPI-DWI的SIR均低于常规EPI-DWI的SIR(1.133 2vs 1.158 6;t=-2.870,P>0.05);④SENSE-EPI-DWI的正常小脑ADC值均高于常规EPI-DWI序列的正常小脑ADC值(t=9.962,P<0.05);⑤SENSE-EPI-DWI的梗死灶/健侧脑组织的比值均高于常规EPI-DWI的梗死灶/健侧脑组织的比值(1.34 vs 1.06;t=5.216,P<0.05)。结论SENSE-EPI-DWI技术的成像质量较高,正常小脑ADC值有助于脑梗死的诊断,且在具有磁化率伪影的脑梗死诊断应用中优于常规的EPI-DWI序列。
Objective To study the application of parallel acquisition (SENSE) combined with planar echo-diffusion-weighted imaging (EPI-DWI) in cerebral infarction with magnetic susceptibility artifacts. Methods The data of 38 patients with fixed metal denture infarction were collected. There were 22 males and 16 females, aged from 52 to 86 years with a mean age of 72 years. MRI skull imaging, diffusion-weighted imaging (DWI) and SENSE-EPI-DWI were performed. The signal intensity contrast (SIR), mean ± standard deviation (RSV), CNR, SIR, normal cerebellum surface diffusion coefficient (SVD) and normal cerebellar cerebrospinal fluid in both right and left cerebrospinal fluid before and after SENSE were compared ADC), ADC ratio of infarct / contralateral brain tissue. Results ① The mean ± standard deviation (SIR) of SIR in right-sided basal ganglia and right-sided cerebrospinal fluid of patients with SENSE-EPI-DWI was higher than that of routine EPI-DWI (0.810 0 ± 0.386 3 vs 0.610 0 ± 0.468 7; = 9.872, P <0.05). (2) The CNR of SENSE-EPI-DWI was higher than that of conventional EPI-DWI (11.622 5 vs 4.385 3; t = 6.615, The normal cerebellum ADC value of SENSE-EPI-DWI was higher than that of normal EPI-DWI (t = 9.962, t = -2.870, P> 0.05) (P <0.05). (5) The ratio of infarction / contralateral brain tissue in SENSE-EPI-DWI group was higher than that in conventional EPI-DWI group (1.34 vs 1.06; . Conclusion The SENSE-EPI-DWI technique has higher imaging quality. The normal cerebellum ADC value is helpful for the diagnosis of cerebral infarction. It is superior to conventional EPI-DWI in the diagnosis of cerebral infarction with magnetic susceptibility artifacts.