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目的分析孕前体质量指数、孕期体质量增加变化与孕期心脏功能的关系。方法选取单胎妊娠并足月分娩的正常初孕妇女180例,根据孕前体质量指数(BMI)分为正常(20kg/m2P85)3个亚组各20例。孕晚期末孕妇进行心脏超声心动图检查及血清脑钠肽(BNP)检查。比较不同孕前体质量指数及孕期不同体质量变化对孕期妇女心力衰竭发病率。结果析因设计的方差分析显示孕前体质量指数与孕期增重变化均为妊娠期妇女心力衰竭患病率增加的危险因素。两因素交互作用分析显示孕前体质量指数超重及肥胖与孕期增重过多均显著影响妊娠期心力衰竭发病率。结论孕前肥胖及超重、孕期体质量增加过多孕妇心脏负荷增加,心力衰竭发病率高。保持孕妇孕期适宜体质量增加有助于控制孕期心力衰竭发病率。
Objective To analyze the relationship between pre-pregnancy body mass index, changes in body mass during pregnancy and cardiac function during pregnancy. Methods One hundred and eighty normal pregnant women with full-term childbirth were enrolled in this study. According to their pre-pregnancy body mass index (BMI), they were divided into normal group (20kg / m2 P85) 3 subgroups of 20 cases. Pregnant women at the end of third trimester were examined by echocardiography and serum brain natriuretic peptide (BNP). The incidence of heart failure in pregnant women was compared between different pre-pregnancy body mass index and different body weight during pregnancy. Results Ananlysis analysis of factorial design showed that pre-pregnancy body mass index and weight gain during pregnancy were both risk factors for the increased prevalence of heart failure in pregnant women. Two-factor interaction analysis showed that pre-pregnancy body mass index overweight and obesity and excessive weight gain during pregnancy significantly affect the incidence of heart failure in pregnancy. Conclusion Pre-pregnancy obesity and overweight, excessive increase in body mass during pregnancy increased cardiac load, high incidence of heart failure. Maintaining pregnant women suitable body mass gain during pregnancy helps to control the incidence of heart failure during pregnancy.