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虽然肺癌有半数病例早期已存在转移(以骨、肝、肾上腺和淋巴结转移常见),但以前仅有9例转移到小肠的报告。本文研究呈在证明肺癌发生隐匿的和有临床表现的小肠转移率。1974年1年—1984年12月美国MCVH和MVAH两间医院在431例原发性肺癌的尸检中,46例有小肠转移。这些病例平均有4.8个转移瘤灶。有小肠转移的病例中,大细胞癌占12/31(39.0％)、腺癌占13/108(12.3％)、小细胞癌占6/73(8.0％),鳞状细胞癌占15/199(7.5％)、20例未分化癌中没有小肠转移。在同一时期,因转移癌而行小肠切除术的78例中,有6例属于原发性肺癌。第1例男性,51岁,右上肺鳞状细胞癌,初诊后33个月,脑脊髓转移
Although half of lung cancer patients had metastases in the early stages (common with bone, liver, adrenal glands, and lymph node metastasis), only 9 cases had previously been reported to the small intestine. This study was conducted to demonstrate the incidence of occult and clinical manifestations of small bowel metastases in lung cancer. During the autopsy of 431 patients with primary lung cancer between January 1974 and December 1984 in the US MCVH and MVAH hospitals, 46 patients had intestinal metastases. These cases have an average of 4.8 metastases. In cases with small bowel metastases, 12/31 (39.0%) of large cell carcinoma, 13/108 (12.3%) of adenocarcinoma, 6/73 (8.0%) of small cell carcinoma, and 15/199 of squamous cell carcinoma. (7.5%) There was no intestinal metastasis in 20 undifferentiated carcinomas. In the same period, of the 78 cases undergoing small bowel resection for metastatic cancer, 6 cases belonged to primary lung cancer. The first case was a 51-year-old man with right upper lung squamous cell carcinoma. The brain metastasis was 33 months after the initial diagnosis.