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三级胺纳洛酮和纳曲酮进行N-脱烷基反应试图得到二级胺去甲羟吗啡酮的反应曾用过氯甲酸乙酯,产率很低。我们正在进一步探索这类反应。
The tertiary amine Naloxone and Naltrexone N-dealkylation reaction attempt to obtain secondary amine noroxymorphone reaction with ethyl chloroformate, the yield is very low. We are exploring this type of reaction further.