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目的测定急性心肌梗死患者压力源性冠脉侧支血流分数(PDCF),评价PDCF与传统的Rentrop分级间的相关性。方法29例急性心肌梗死患者行介入术,术中应用冠脉内压力导丝根据Pw/Pa计算PDCF,以0.24为PDCF截值将29例分为2组:A组(19例)PDCF>0.24,B组(10例)PDCF≤0.24。术后根据冠脉造影行Rentrop分级。使用统计学方法对数据进行线性回归分析,讨论PDCF与Rentrop分级间的相关性。结果Rentrop分级同PDCF呈正相关(r=0.75,P<0.01),但Rentrop≤1级的PDCF分布范围较为离散。结论冠脉内压力源性PDCF测量可对AMI时侧支循环血流作出定量评价。
Objective To determine the pressure-dependent coronary collateral flow fraction (PDCF) in patients with acute myocardial infarction and evaluate the relationship between PDCF and the traditional Rentrop classification. Methods Twenty-nine patients with acute myocardial infarction underwent the interventional procedure. The intra-arterial pressure catheter was used to calculate PDCF according to Pw / Pa. The PDCF cut-off value of 0.24 was used to divide 29 patients into two groups: group A (n = 19), PDCF> , Group B (10 cases) PDCF≤0.24. Postoperative Rentrop grading according to coronary angiography. The data were analyzed by linear regression using statistical methods and the correlation between PDCF and Rentrop grade was discussed. Results The Rentrop grade was positively correlated with PDCF (r = 0.75, P <0.01), but the distribution range of Rentrop≤1 grade PDCF was more discrete. Conclusions Intracoronary pressure-derived PDCF measurement can quantitatively assess collateral flow in AMI.