妊高征的基本病理生理变化是全身小动脉痉挛。患者在出现临床症状数周及数月前，对血管紧张素正的敏感性增强，血管紧张素可直接作用于血管壁使其收缩，加之血小板、纤维蛋白原通过损伤的血管内皮沉积其下，使小动脉管腔狭小，外周阻力增加。血管内皮是位于血液与血管平滑肌纤 PIH basic pathophysiological changes of systemic arteriolar spasm. Patients in clinical symptoms of a few weeks and a few months ago, positive angiotensin sensitivity increased, angiotensin can act directly on the vessel wall to shrink, in addition to platelets, fibrinogen through the damaged vascular endothelial deposition, Small arterial lumen narrowing, peripheral resistance increased. Endothelium is located in the blood and vascular smooth muscle fibers