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目的:甲状腺激素,主要以甲状腺素(T_4)的形式分泌。在肝及肾脏等末梢组织中,通过5′—脱碘酶的作用进行脱碘,成为3,5,3′—三碘甲腺原氨酸(T_3),发挥激素作用。这种酶可以通过二硫苏糖醇(di-throthreidol)和还原谷胱甘肽等具有 SH 基
Objective: Thyroid hormone, mainly in the form of thyroid hormone (T_4) secretion. In peripheral tissues such as the liver and the kidney, deiodination is performed by the action of 5’-deiodinase to become 3,5,3’-triiodothyronine (T_3), which acts as a hormone. This enzyme can be activated by dithiothreitol (di-throthreidol) and reduced glutathione and other SH-based