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背景:循环血内皮祖细胞(EPC)会在缺血时增加,并可能促进新生血管生成。EPC水平还能预测动脉粥样硬化性疾病患者的临床结局。本研究拟验证如下假说:循环血EPC能预测充血性心力衰竭(CHF)患者的临床结局。方法:以107例纽约心脏协会(NYHA)心功能分级II～IV级的连续CHF患者为研究对象,检测其外周血的EPC集落成形单位。
Background: Circulating endothelial progenitor cells (EPCs) increase during ischemia and may promote neovascularization. EPC levels also predict the clinical outcome of patients with atherosclerotic disease. This study is to test the hypothesis that circulating blood EPC can predict the clinical outcome of patients with congestive heart failure (CHF). Methods: A total of 107 consecutive patients with NYHA cardiac function class II-IV CHF were enrolled in this study. EPC colony forming units of peripheral blood were detected.