目的 :研究观察扭伤灵搽剂的皮肤刺激性。方法 :对健康家兔脱毛后多次性给予扭伤灵搽剂、赋形剂 ,评分标准按“中药新药临床前研究指导原则”中的相关内容 ,对实验结果加以评定。结果 :家兔多次性涂用扭伤灵搽剂后完整皮肤刺激未见异常改变 ,破损皮肤涂药部位亦未出现红斑、水肿、出血点、色素沉着以及皮肤粗糙等。结论 :本品在临床应用中是一种安全性较好的外用制剂 Objective: To study the skin irritation of sprained splints. Methods: Several times after the hair removal, healthy rabbits were given sprains, sputum, and excipients. The scoring criteria were evaluated according to the relevant content in the “Guidelines for preclinical research of new Chinese medicines”. RESULTS: No abnormal changes were found in the intact skin irritation after the rabbits had been sprung with sprained spirulina for several times, and the erythema, edema, bleeding points, pigmentation, and rough skin were not found on the damaged skin. Conclusion : This product is a safe topical preparation for clinical use