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目的从微小RNA-203(micro RNA-203,mi R-203)的生成、组织分布以及其与肿瘤的关系方面对其做一综述。方法通过查阅并筛选国内外的相关文献,归纳并总结有关mi R-203的生成、组织分布及其与肿瘤关系的最新研究情况。结果尽管目前有关mi R-203在恶性肿瘤中的作用的研究结果令人振奋,但是只有mi R-203的少部分生物学功能得到了鉴定,与之相对应的下游靶基因的调控机制亦尚未完全阐明。结论随着相关研究的不断深入,mi R-203有可能在肿瘤的分级、分类、诊断、治疗及预后方面起到更加积极的作用。
OBJECTIVE: To summarize the generation and distribution of micro RNA-203 (mi R-203) and its relationship with tumor. Methods By reviewing and screening relevant literatures at home and abroad, the latest research on the generation and distribution of mi R-203 and its relationship with tumor was summarized and summarized. Results Although the current findings on the role of mi R-203 in malignant tumors are encouraging, only a small fraction of the biological function of mi R-203 has been identified, and the underlying downstream target gene regulation mechanisms have not been identified Completely clarified. Conclusion With the continuous deepening of relevant research, mi R-203 may play a more active role in the classification, classification, diagnosis, treatment and prognosis of tumors.