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目的探讨宫腔规整对首次IVF-ET失败者子宫内异常诊断和治疗的重要性。方法随机选取2012年4月-2015年4月收治的53例首次IVF-ET失败患者,依据检查方法将这些患者分为两组,即研究组(32例)和对照组(21例)。给予研究组患者经阴道超声检查联合宫腔镜检查,对照组患者不给予经阴道超声联合宫腔镜检查。结果研究组患者阴道超声检查和宫腔镜检查内膜息肉、内膜炎、内膜增生症、黏膜下肌瘤、子宫中隔等子宫内异常检出率之间的差异均不显著(P>0.05),临床妊娠率(54.2%,13/24)显著高于对照组(28.6%,6/21)(P<0.05),但两组患者的h CG日内膜厚度、获卵数、移植胚胎数之间的差异均不显著(P>0.05)。结论宫腔规整能够有效排除首次IVF-ET失败者子宫内异常,提升妊娠率。
Objective To investigate the importance of uterine regularity in the diagnosis and treatment of uterine abnormalities in the first failure of IVF-ET. Methods 53 patients with first failure of IVF-ET admitted from April 2012 to April 2015 were randomly divided into two groups: study group (32 cases) and control group (21 cases). Patients in the study group were given transvaginal ultrasonography combined with hysteroscopy, and patients in the control group were not given transvaginal sonography combined with hysteroscopy. Results There was no significant difference in the detection rate of intrauterine anomalies among the patients with endometrial polyps, endometritis, endometrial hyperplasia, submucosal fibroids and uterine septum in vaginal ultrasonography and hysteroscopy (P> 0.05). The clinical pregnancy rate (54.2%, 13/24) was significantly higher than that of the control group (28.6%, 6/21) (P <0.05) There was no significant difference between embryo numbers (P> 0.05). Conclusion The regular uterine cavity can effectively rule out the first abnormal IVF-ET intrauterine abnormalities, improve pregnancy rate.