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目的:探讨胚宝胶囊联合来曲唑治疗排卵障碍性不孕症的效果及对患者血清性激素水平的影响。方法:选择台州市肿瘤医院2017年1月至2019年12月收治的排卵障碍性不孕症患者60例，按照随机数字表法分为观察组（30例）与对照组（30例），对照组患者给予来曲唑治疗，观察组患者给予胚宝胶囊联合来曲唑治疗。两组患者均于月经周期第5天开始服药，连服5 d，共3个周期。比较两组治疗前后优势卵泡直径、子宫内膜厚度、卵巢动脉阻力指数和搏动指数、血清性激素水平变化，及排卵率和妊娠率。结果:观察组治疗后优势卵泡直径（18.41±0.54）mm和子宫内膜厚度（8.79±0.56）mm，均高于对照组的（17.79±0.47）mm和（7.82±0.62）mm（n t=4.744、6.359，均n P<0.05）；观察组治疗后卵巢动脉阻力指数（0.97±0.13）和搏动指数（0.56±0.04），均低于对照组的（1.08±0.10）和（0.65± 0.04）（n t=3.674、8.714，均n P<0.05）；观察组治疗后血清孕酮（0.93±0.14）μg/L、雌二醇（75.41±6.29）ng/L和黄体生成素（9.47±0.61）IU/L，均高于对照组的（0.78±0.12）μg/L、（58.23±5.46）ng/L和（8.18±0.65）IU/L（n t=4.456、11.297、7.926，均n P<0.05）；观察组排卵率［60.00%（18/30）］和妊娠率［46.67%（14/30）］均高于对照组［33.33%（10/30）］和［23.33%（7/30）］（χn 2=4.286、3.897，均n P<0.05）。n 结论:胚宝胶囊联合来曲唑治疗排卵障碍性不孕症效果明显，可改善患者血清性激素水平，促进排卵和提高妊娠率。“,”Objective:To investigate the efficacy of n Peibao capsules combined with letrozole in the treatment of ovulatory infertility and its effects on serum sex hormone levels.n Methods:Sixty patients with ovulatory infertility who received treatment in Taizhou Cancer Hospital from January 2017 to December 2019 were included in this study. They were randomly assigned to receive treatment with either letrozole (control group, n n = 30) or n Peibao capsules combined with letrozole (observation group, n n = 30) starting at the 5n th day of the menstrual cycle for 5 days, totally 3 menstrual cycles. Before and after treatment, dominant follicle diameter, endometrial thickness, ovarian artery resistance index and pulsatility index, serum sex hormone level, ovulation rate and pregnancy rate were compared between the control and observation groups.n Results:After treatment, dominant follicle diameter and endometrial thickness in the observation group were (18.41 ± 0.54) mm and (8.79 ± 0.56) mm, respectively, which were significantly greater than those in the control group [(17.79 ± 0.47) mm and (7.82 ± 0.62) mm, n t = 4.744 and 6.359, both n P < 0.05]. After treatment, ovarian arterial resistance index and pulsatility index in the observation group were 0.97 ± 0.13 and 0.56 ± 0.04, respectively, which were significantly lower than those in the control group [1.08 ± 0.10 and 0.65 ± 0.04, n t = 3.674, 8.714, both n P < 0.05]. After treatment, serum progesterone, estradiol and luteinizing hormone in the observation group were (0.93 ± 0.14) μg/L, (75.41 ± 6.29) ng/L and (9.47 ± 0.61) IU/L, respectively, which were significantly higher than those in the control group [(0.78 ± 0.12) μg/L, (58.23 ± 5.46) ng/L and (8.18 ± 0.65) IU/L, n t = 4.456, 11.297, 7.926, all n P < 0.05]. Ovulation rate and pregnancy rate in the observation group were 60.00% (18/30) and 46.67% (14/30), respectively, which were significantly higher than those in the control group [33.33% (10/30) and 23.33% (7/30), χ n 2 = 4.286, 3.897, both n P < 0.05).n Conclusion:Peibao capsules combined with letrozole is highly effective in the treatment of ovulatory infertility. It can improve patient's serum sex hormone level, promote ovulation, and increase pregnancy rate.n