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目的 探讨门诊消化道内镜患者术后疲劳综合征(POFS)的发生情况.方法 选取2016年10月至2017年2月江苏省苏北人民医院收治的500例行胃镜检查的连续门诊患者和252例行结肠镜检查的连续门诊患者,根据是否麻醉分为无痛胃镜组、普通胃镜组、无痛结肠镜组、普通结肠镜组.4组患者均行常规操作.无痛胃镜组静脉注射丙泊酚麻醉.无痛结肠镜组静脉注射丙泊酚和地佐辛.评估各组检查后POFS发生率、初始疲劳程度和持续时间.结果 无痛胃镜组POFS发生率(28.0％)高于普通胃镜组(4.7％),初始疲劳评分[(5.19±2.36)分]高于普通结肠镜组[(3.17±0.58)分],差异均有统计学意义(P<0.05).无痛结肠镜组POFS发生率(48.0％)高于普通结肠镜组(6.4％),POFS持续时间[(9.16±9.94)h]低于普通结肠镜组[(31.31±32.00)h],差异均有统计学意义(P<0.05).无痛胃镜组POFS发生概率、初始疲劳评分低于无痛结肠镜组;普通胃镜组初始疲劳评分、持续时间低于普通结肠镜组,差异均有统计学意义(P<0.05).结论 接受消化道内镜检查的患者会出现POFS,接受无痛消化道内镜患者的POFS发生率、严重程度显著高于接受普通消化道内镜的患者.“,”Objective To investigate the postoperative fatigue syndrome ( POFS) of outpatient di-gestive endoscope. Methods A retrospective study was performed on 500 cases of out-patients underwent gastroscopy and 252 cases of the ones underwent colonoscopy from October 2016 to February 2017. According to whether anesthesia was performed or not,patients were divided into the painless gastro-scope group,general gastroscope group,painless colonoscope group and general colonoscope group. The inci-dence,initial fatigue and duration of POFS were assessed. Results The incidence of POFS in painless gas-troscope group ( 28. 0％) was higher than ( 4. 7％) in general gastroscope group, the initial fatigue rating [(5. 19 ± 2. 36)points]was higher than[(3. 17 ± 0. 58)points]in general gastroscope group,with statis-tically significant differences (P<0. 05). The incidence of POFS in painless colonoscope group (48. 0％) was higher than (6. 4％)in general colonoscope group,and the duration of POFS[(9. 16 ± 9. 94)hours] was shorter than[(31. 31 ± 32. 00)hours]in general colonoscope group,with statistically significant differ-ences (P<0. 05). Incidence of POFS and initial fatigue score in painless gastroscope group were signifi-cantly lower than those in painless colonoscope group. Initial fatigue score and duration in the general gas-troscope group were significantly lower than those in the general colonoscope group,with statistically signifi-cant differences (P<0. 05). Conclusion Conclusion POFS does exist after digestive endoscopy,and the occurrence probability and severity of POFS in painless digestive endoscopy patients is significantly higher than that in general gastrointestinal endoscopy patients.