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目的 超声引导穿刺 (USGP)经腹或阴道介入性治疗卵巢子宫内膜异位囊肿 ,并对注入囊内不同药物进行对比研究 ,从中筛选出高效、副作用小的药物。方法 114例患者共 118个囊肿 ,其中子宫内膜异位囊肿 86个 ,对照组卵巢单房囊肿 3 2个 ,各分成 3组和 2组。分别用无水酒精 (E1组、C1组 )、2 .5 %～ 5 .0 %四环素溶液 (E2 组、C2 组 )、15 0mg/ml狄波 -普维拉 (E3 组 )注入囊肿治疗 ,术后半年内随访评价囊肿缩小情况。结果 子宫内膜异位囊肿组治愈率 :E1组 91.4% ( 3 2 /3 5 ) ,E2 组 64 % ( 16/2 5 ) ,E3 组84.6% ( 2 4/2 6) ,三组间差异有显著性意义 (P <0 .0 5 )。但三组的治愈显效率差异无显著性意义 (P >0 .0 5 )。卵巢单房囊肿组治愈率 :C1组与C2 组均为 10 0 %。囊肿越大治愈所需时间越长。结论 超声引导穿刺治疗子宫内膜异位囊肿是一种高效、可靠、安全和经济的方法 ,所用三种药物均有显著效果 ,普维拉无刺激性 ,又有治疗子宫内膜异位症的作用 ,值得推广应用。
OBJECTIVE: Ultrasound-guided puncture (USGP) transvaginal or vaginal interventional treatment of ovarian endometriotic cysts, and comparative study of different drugs injected into the capsule, from which screening of high efficiency, small side effects of drugs. Methods One hundred and fourteen patients with 118 cysts, including 86 endometriotic cysts and 32 ovarian single-cell cysts in the control group were divided into 3 groups and 2 groups. Cysts were treated with anhydrous alcohol (group E1, group C1), 2.5% -5.5% tetracycline solution (group E2, group C2) and 15 0 mg / ml Depo- Follow-up within six months after surgery to assess the shrinkage of the cyst. Results The cure rate of endometriosis cyst group was 91.4% (3 2/3 5) in E1 group, 64% (16/2 5) in E2 group and 84.6% (2 4/2 6) in E3 group There was significant (P <0. 05). However, there was no significant difference between the three groups in curative effect (P> 0.05). Ovarian single room cyst group cure rate: C1 group and C2 group were 100%. Larger cysts cure longer. Conclusion Ultrasound-guided puncture for endometriotic cysts is an efficient, reliable, safe and economical method. All the three drugs used have significant effects. Puvira is non-irritating and has the potential to treat endometriosis Role, it is worth promoting application.