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研究了225例正常晚孕者和妊娠高血压综合征(妊高征)患者的抗凝血酶Ⅲ(ATⅢ)活性、纤维蛋白原(Fg)、纤维蛋白降解产物(FDP)和尿酸的改变。结果表明,ATⅢ具有最高的判别效率,在多数妊高征患者中,ATⅢ活性低于对照组一个标准差,选择ATⅢ活性低于80%为本病的预测值,ATⅢ预测本病的敏感性和特异性分别为71%和82%。与尿酸测定比较,ATⅢ活性预测准确性较高,可成为诊断本病一项有实用价值的指标,
To investigate the changes of antithrombin Ⅲ (ATⅢ) activity, fibrinogen (Fg), fibrin degradation products (FDP) and uric acid in 225 normal pregnant women and patients with pregnancy induced hypertension (PIH). The results showed that AT Ⅲ had the highest discriminative efficiency. In most patients with PIH, the activity of AT Ⅲ was lower than that of the control group by one standard deviation. The ATⅢ activity was less than 80% as the predictive value. AT Ⅲ predicted the sensitivity of the disease and The specificity was 71% and 82% respectively. Compared with the determination of uric acid, AT Ⅲ activity prediction accuracy is high, can become a diagnosis of the disease has a practical value index,