Fanconi氏综合征是一种比较罕见的疾病,主要表现为多发性先天畸形、全血细胞减少和骨髓再生障碍。本病自Fanconi氏(1927)首次报告以来,国外文献屡有报导,至目前为止,大约有80多例,国内仅严氏等于1963年报告1例。我院于1957年曾见1例,死后并经尸体解剖证实,兹报告如下。患儿林某(住院号29103),女性,7岁,广东南海籍,因进行性面色苍黄1月余,于1957年7月13日入院。患儿于出生后即发现全身皮肤棕黑,于入院前1月余突流鼻血约100毫升,数日后伴有发热、咳 Fanconi’s syndrome is a relatively rare disease, mainly manifested as multiple congenital malformations, pancytopenia and bone marrow regeneration disorders. Since the first report of Fanconi’s (1927), this disease has been reported frequently in foreign countries. So far, about 80 cases have been reported in this disease and only 1 case reported in 1963 in China. One case was seen in our hospital in 1957, after death and confirmed by autopsy, hereby report as follows. Children Lin (hospital number 29103), female, 7 years old, Guangdong South China Sea, progressive pale yellow due to more than January, on July 13, 1957 admitted. Children found after birth that the body skin brown black, in January before admission I nosebleed nosebleed about 100 ml, a few days later with fever, cough