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目的探讨普通超声及超声造影预测甲状腺微小乳头状癌(PTMC)中央区淋巴结转移(CCLNM)的价值。方法选取我院经手术病理证实的63例PTMC患者,分为CCLNM组20例,无CCLNM组43例。回顾性分析并比较两组患者的术前普通超声及超声造影特征,分析其各个特征与CCLNM的关系。结果单变量分析表明PTMC和CCLNM有关的因素包括肿瘤直径>0.5cm、侵犯包膜、边界不清、微钙化、高或等增强模式(P均<0.05)。多变量分析表明肿瘤侵犯包膜和微钙化与CCLNM有相关性(P均<0.05)。结论肿瘤侵犯包膜、微钙化对PTMC患者中央区淋巴结转移有一定的预测价值,有助于临床诊断和治疗。
Objective To investigate the value of conventional ultrasound and contrast-enhanced ultrasound in the prediction of central lymph node metastasis (CCLNM) in thyroid papillary carcinoma (PTMC). Methods Totally 63 PTMC patients confirmed by pathology in our hospital were divided into CCLNM group (n = 20) and CCLNM group (n = 43). Retrospective analysis and comparison of the two groups of patients preoperative ultrasound and contrast-enhanced ultrasound features, analysis of its various characteristics and CCLNM relationship. Results Univariate analysis showed that PTMC and CCLNM related factors include tumor diameter> 0.5cm, invasion of envelope, unclear boundary, microcalcification, high or equal enhancement mode (all P <0.05). Multivariate analysis showed that tumor invasion and microcalcifications were associated with CCLNM (all P <0.05). Conclusion Tumor invasion of envelope and microcalcification have some predictive value in the central lymph node metastasis of PTMC patients, which is helpful for clinical diagnosis and treatment.