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异名 Lustral 化学名 (1S,4S)-4-(3,4-二氯苯基)-1,2,3,4-四氢-N-甲基-1-萘胺盐酸盐药效分类抗抑郁药上市厂商 (英)辉瑞公司Invicta药厂1990年11月在英国上市三环类抗抑郁药治疗内源性抑郁症是根据该症系脑内去甲肾上腺素和5-羟色胺活性失衡的理论。较老的抗抑郁药抑制这两种物质的吸收,有时主要抑制去甲肾上腺素的吸收,因此增加去甲肾上腺素能神经传递,但对5-羟色胺机制的影响较小.很多三环类药
Synonyms Lustral chemical name (1S, 4S) -4- (3,4-dichlorophenyl) -1,2,3,4-tetrahydro-N-methyl-1-naphthylamine hydrochloride Pharmacodynamic classification Antidepressants listed manufacturers (UK) Pfizer Invicta Pharmaceuticals listed in the United Kingdom in November 1990 Tricyclic antidepressants treatment of endogenous depression is based on the disorder of brain norepinephrine and serotonin activity imbalance theory. Older antidepressants inhibit the absorption of these two substances, and sometimes predominately inhibit the absorption of norepinephrine, thus increasing norepinephrine neurotransmission, but with less effect on the serotonin mechanism.Many tricyclics