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鳞柱状上皮交界处肠化而没有Barrett食管是常见的,但它与胃食管反流病和腺癌的关系尚不清楚。为此对作诊断性胃镜检查的病人进行研究以估价与此相关的临床、内镜和组织学改变。 方法:随机选择病人作常规诊断性胃镜检查,剔除已知有Barrett食管、以前曾做过内镜检查、有胃食管手术史、服用华法令伴食管静脉曲张或病情危重以及需要进行治疗者。记录门齿至鳞柱状上皮交界处、胃皱襞近缘、膈疝和胃开口的距离,然后每例取8块粘膜活检作组织学分析。其中鳞柱状上皮交界处上方2cm 1块;
It is common for intestinal metaplasia at the junction of squamous epithelium without Barrett’s esophagus, but its relationship to gastroesophageal reflux disease and adenocarcinoma remains unclear. For this purpose, patients undergoing diagnostic endoscopy were studied to assess the clinical, endoscopic and histological changes associated with this. Methods: Patients were randomly selected for routine diagnostic endoscopy, excluding known Barrett’s esophagus, previously performed endoscopy, history of gastroesophageal surgery, warfarin with esophageal varices or critically ill patients and the need for treatment. Record incisors to squamous epithelium at the junction of the stomach folds proximal edge of the diaphragmatic hernia and the opening of the stomach, and then take 8 mucosal biopsies for each case for histological analysis. One squamocoloid epithelium at the junction of 2cm 1 block;