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目的探讨低分子右旋糖酐40在慢性病毒性(乙型)肝炎(重度)(以下简称重度乙肝)治疗中对胆红素降低的效果。法2005年～2009年我院61例符合2005年西安会议慢性病毒性(乙型)肝炎(重度)诊断标准的病例随机分为A、B两组,分别给予对重度肝炎内科治疗基础上加用低分子右旋糖酐40和只用重度肝炎基础内科治疗,对治疗组和对照组治疗前、治疗2周总胆红素下降进行统计学分析。结果 A组比B组胆红素下降明显有统计学意义(p<0.05)。结论低分子右旋糖酐在重度乙肝治疗中能起到明显退黄作用。
Objective To investigate the effect of low molecular weight dextran 40 on the decrease of bilirubin in the treatment of chronic viral hepatitis B (severe) (hereinafter referred to as severe hepatitis B). Methods From 2005 to 2009, 61 cases of chronic hepatitis B (hepatitis B) diagnostic criteria in our hospital from 2005 to 2009 were randomly divided into A and B groups, which were treated with medical treatment of severe hepatitis with low Molecular dextran 40 and only basic medical treatment of severe hepatitis, the treatment group and control group before treatment, total bilirubin 2 weeks after treatment decreased. Results The decrease of bilirubin in group A was more significant than that in group B (p <0.05). Conclusion Low molecular dextran can play a significant role in the treatment of severe hepatitis B.