作者相继发现2例军团菌感染伴有斑丘疹和严重肾衰竭(需行血液透析)的罕见病例。病例1为1名67岁居住在退伍军人管理局(VA)宿舍的男性患者,因跌倒后额部撕裂,受检于VA医学中心分会。体温39.1℃,胸透双侧肺部浸润。痰标本直接荧光抗体染色发现军团菌,痰培养分离出军团菌1型(knoxville)。于48小时内在躯干和四肢发现弥散性红疹、斑丘疹。虽给予静注红霉素,仍发展为急性呼吸衰竭需行机械通气, The authors found two rare cases of Legionella infection associated with rash and severe renal failure (hemodialysis required). Case 1 A male patient aged 67 and living in a Veterans Administration (VA) dorm room was torn by a forehead drop and was examined at the VA Medical Center Branch. Body temperature 39.1 ℃, chest through bilateral lung infiltration. Sputum specimens were stained with a fluorescent antibody to detect Legionella and sputum culture to isolate the knoxville. Diffuse rash and rash on the trunk and extremities were found within 48 hours. Although given intravenous erythromycin, still develop acute respiratory failure need mechanical ventilation,