论文部分内容阅读
目的 :研究哮喘患儿发作期与缓解期血清IL 1 2、IL 6与IgE水平。 方法 :选择符合哮喘诊断标准发作期患儿 2 5例 ,缓解期患儿 1 1例 ,取其静脉血检测血清IL 1 2、IL 6和IgE水平。 结果 :发作期IL 1 2水平明显降低 ,与缓解期比较差异有显著意义 (P <0 .0 5)。发作期IgE水平明显升高 ,与缓解期比较差异也有显著意义 (P<0 .0 5)。IL 6水平在发作期升高 ,缓解期下降 ,但两者比较差异无显著意义 (P >0 .0 5)。结论 :小儿哮喘是一种慢性气道炎症 ,在缓解期仍需抗炎治疗
Objective: To study the serum levels of IL-12, IL-6 and IgE in attacking and remission stages of asthmatic children. Methods: Twenty-five children with acute asthma and 11 children with remission were enrolled. Serum levels of IL-12, IL-6 and IgE were measured by venous blood. Results: The level of IL-12 in the attack stage was significantly lower than that in the remission stage (P <0.05). IgE levels were significantly increased during the attack, and the difference was also significant compared with the remission (P <0.05). The levels of IL-6 increased during the attack and decreased during the remission, but there was no significant difference between the two (P> 0.05). Conclusion: Pediatric asthma is a chronic airway inflammation that still needs anti-inflammatory treatment during remission